- Author
-
Humphrey, B. J.
|
Smith, B. R.
|
Skaggs, S. R.
- Title
- Toxicity of Halon 2402. Final Report. August 1985-September 1986.
- Coporate
- New Mexico Engineering Research Inst., Albuquerque, NM
- Sponsor
- Air Force Engineering and Services Center, Tyndall AFB, FL
- Report
-
ESL-TR-88-59; WA3-82(3.18),
September 1990,
42 p.
- Contract
- F29601-C-85-0080
- Keywords
-
toxicity
|
halon 2402
|
halon 1211
|
acute toxicity
|
rats
|
inhalation
- Abstract
- The acute toxicity of Halon 2402 was assessed and compared to that of Halon 1211. Separate lots of Fischer-344 rats were exposed for 4 hours by inhalation to various concentrations of either Halon 2402 or 1211. The Maximum Tolerated Concentration, Approximate Lethal Concentration, and No Observable Effect Level were determined for each agent. Test animals were clinically observed daily for 14 days after exposure and euthanized. Tissues were examined for histopathological changes. This study indicates that Halon 2402 is more toxic than Halon 1211. It was difficult, however, to conclude that any pathological findings were a direct result of the test agents.