- Author
- Hartzell, G. E. | Priest, D. N. | Switzer, W. G.
- Title
- Mathematical Modeling of Toxicological Effects of Fire Gases.
- Coporate
- Southwest Research Inst., San Antonio, TX
- Sponsor
- National Bureau of Standards, Gaithersburg, MD
- Contract
- NBS-GRANT-NB83NADA4015 SRI-PROJECT-01-9316
- Book or Conf
- International Association for Fire Safety Science. Fire Safety Science. Proceedings. 1st International Symposium. Gaithersburg, MD. Hemisphere Publishing Corp., New York. Grant, C. E. and Pagni, P. J., Editors. TH9112.F5626 1986. 1059-1068 pgs. October 7-11, 1985 AND UJNR Panel on Fire Research and Safety. 8th Joint Panel Meeting. 683-708 pgs. Tsukuba, Japan. May 13-21, 1985, 1986
- Keywords
- combustion toxicology | mathematical models
- Abstract
- Research in combustion toxicology over the past few years has led to a reasonable understanding and even quantification of some of the effects of fire effluent toxicants and, with the availability of a modest amount of both non-human primate and human exposure data, the combustion toxicologist is gaining increasing capability to assess and predict the toxicological effects of smoke inhalation. This paper presents a mathematical approach, based on experimental data for CO, HCN and HCl, for the prediction of both incapacitating and lethal effects of rats exposed to these toxicants. Elementary examples are given for computer simulation of the development of toxic hazards in fires and comparisons are made with actual experimental results. These comparisons show that computer-predicted times to toxicological effects lie within the standard deviation of experimental mean values.