- Author
- Burns, D. M.
- Title
- Assessing Changes in Topography (Inhalation Profile) and Biological Effects of Tobacco Smoke in Humans.
- Coporate
- San Diego Medical Center, CA
- Sponsor
- Consumer Product Safety Commission, Washington, DC
- Report
- Volume 5, August 1993,
- Distribution
- Available from U.S. Consumer Product Safety Commission, Washington, DC 20207
- Contract
- CPSC-S-92-5472
- Keywords
- cigarettes | topography | smoke | human beings | smoke yield | smoking | ignition
- Identifiers
- inhalation profile; biological effects; tobacco smoke
- Abstract
- The most useful approaches in the evaluation of differences in risks between presently marketed and low-ignition-potential cigarettes focus on chemical analyses of the cigarette smoke, measures of smoke absorption, and assays in biological systems. Because of practical constraints, human epidemiologic studies would be of very limited practical value. Although the ideal database would derive from prospective human epidemiologic studies, at least twenty years of observation would be needed to collect sufficient data on seriously adverse health effects. Also, if small differences in toxicity are expected, then large sample populations would be needed.