- Author
-
Malek, D. E.
- Title
- New Models to Assess Behavioral and Physiological Performance of Animals During Inhalation Exposures.
- Coporate
- Pittsburgh Univ., PA
- Sponsor
- National Institute of Standards and Technology, Gaithersburg, MD
- Report
-
NIST GCR 88-551
October 1988
163 p.
- Distribution
- Available from National Technical Information Service
- Contract
- NIST-GRANT-60-NANB4001
- Keywords
-
toxicity
|
carbon monoxide
|
animals
|
human behavior
|
hydrogen chloride
|
toxic gases
|
toxicity test methods
- Abstract
- Previously the toxicity of fire smoke has been examined primarily in sedentary animals and lethality was noted. The evaluation of escape potential from a toxic environment, however, requires the measurement of sublethal responses in active animals that are escape predictive. To address this need the mouse tract model and the guinea pig ergometer model have been developed.