- Author
- Bouley, G. | Dubreuil, A. | Jouany, J. M. | Boudene, C.
- Title
- Effet du pyrolysat de matiere plastique polypropylenique sur les mechanismes de defense de l'appareil respiratorire. [Effect of Pyrolysis Products of Polypropylene Plastic on the Defence Mechanisms of the Respiratory System.]
- Coporate
- Laboratoire de Toxicologie, Chatenay-Malabry, France Institut Europeen d'Ecologie de Metz, France
- Journal
- Bull. Europ. Physiopath. Res., Vol. 17, No. 6, 903-910, 1981
- Keywords
- respiratory system | pyrolysis products | polypropylene | plastics | animals
- Identifiers
- airborne infection
- Abstract
- [ABSTRACT IN ENGLISH] Since the use of plastic materials, a change in the pathology of fire victims has been observed. We studied the effects of a single short-term inhalation (30 min) of a sub-lethal dose of polypropylene pyrolysis products (one LD-0). Including control and test animals, 66 rats and 112 mice were used. The exposure provoked distrubances in the antixenic defense mechanisms of the respiratory system, chiefly in tracheo-bronchial defenses, since we observed a lowering of ciliary activity of 35 to 78% in test animals exposed a few hours before, compared with the controls.