- Author
- Vinegar, A. | Jepson, G. W. | Rubenstein, R. | Brock, W. J.
- Title
- Setting Safe Acute Exposure Limits for Halon Replacement Chemicals Using Physiologically Based Pharmacokinetic Modeling.
- Coporate
- Man Tech Environmental Technology, Wright-Patterson AFB, OH Great Lakes Chemical Corp., West Lafeyette, IN Environmental Protection Agency, Washington, DC DuPont Company, Newark, DE
- Journal
- Insulation Toxicology, Vol. 12, No. 8, 751-763, August 2000
- Keywords
- halon alternatives | exposure | blood | human beings | cardiac effects | simulation | halon 1301 | Monte Carlo method
- Identifiers
- Physiologically Based Pharmacokinetic (PBK) modeling; lowest-observed-adverse-effect level (LOAEL) for cardiac sensitization; target arterial concentrations of chemical in blood; chemical-specific model parameters and values