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Author
Vinegar, A. | Jepson, G. W.
Title
Physiologically Based Modeling of Halon Replacements for Human Safety Evaluation.
Coporate
ManTech Environmental Technology, Inc., Dayton, OH
Report
Final Report; Section 1 of 2, 69 p.
Book or Conf
Toxicological Assessment of Human Health Consequences Associated With Inhalation of Halon Replacement Chemicals. Next-Generation Fire Suppression Technology Program (NGP). Final Report. Project 3B/1/89. Section 1 of 2. April 3, 2000, 2000
Keywords
halon alternatives | human beings | safety evaluation | Monte Carlo method | simulation | exposure time | halon 1301 | halon 1211 | inhalation | cardiac effects | chemical agents
Identifiers
requirements for conducting Monte Carlo simulations for establishing safe exposure times for potential halon neplacements agents; setting safe acute exposure limits for halon replacement chemicals using physiologically-based pharmacokinetic modeling; modeling cardiac sensitization potential of humans exposed to halon 1301 and halon 1211 aboard aircraft; physiologically based pharmacokinetic model for simulating breath-by-breath inhalation